Back pain. On day three I had a headache and felt heavy/exhausted, which lasted a few days. (A medication class describes a group of drugs that work in the same way.). Upset stomach or throwing up. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. So theres no recommended pediatric dosage for Injectafer. ByDr. Also tell them about any vitamins, herbs, and supplements you use. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Venofer treatment may be repeated if iron deficiency reoccurs. Following an LSD trip, users may experience a sort of 'comedown.'. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. There are currently no generic forms of either drug. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. An LSD comedown is when the mental and hallucinatory effects have worn . I actually was constipated after my 3rd but didn't think anything of it. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). The iron released by this drug does pass into human breast milk. Yes, in some cases it may. However, consuming large amounts of alcohol can actually cause anemia in some people. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes During Injectafer treatment, your doctor will likely order blood tests. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. The insurance company will review the prior authorization request and decide if the drug will be covered. This information should not be used to decide whether or not to take Venofer or any other medicine. cough. Discuss the risks and benefits with your doctor. This can be very helpful in . Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. In the US - Call your doctor for medical advice about side effects. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. administered at your doctors office or an infusion center. (And Injectafer is used to treat IDA.) During pregnancy, this medication should be used only when clearly needed. Its responsible for carrying oxygen throughout your body. fever. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. Together, they can recommend ways to help you manage a body weight thats healthy for you. Things to remember when you fill your prescription. This medication passes into breast milk. Keep all drugs out of the reach of children and pets. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Throw away unused or expired drugs. Its possible that after getting two doses of Injectafer, your anemia may go away completely. If youre interested in finding an alternative to Injectafer, talk with your doctor. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Do not double the dose to catch up. Venofer® (iron sucrose injection, USP) is available by prescription only. Its responsible for carrying oxygen throughout your body. Version: 7.01. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. There have also been reports of serious allergic reactions to Venofer. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. This is not a complete list of side effects and others may occur. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Keep all medications away from children and pets. Youll receive doses of either drug by a healthcare professional at a medical facility. Its not known whether its safe to breastfeed while youre taking Injectafer. % Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Check with your pharmacist. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Many people using this medication do not have serious side effects. Injectafer and Venofer are both brand-name drugs. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. A healthcare provider will give you this injection. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. Not all possible drug interactions are listed here. intense abdominal pain. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Pain in your limbs. Other drugs are available that can treat iron deficiency anemia (IDA). Procedure Details No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. It is given into a vein for a period of time. . These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. Weight changes may be due to symptoms of anemia improving. weakness. * This is a partial list of mild side effects from Injectafer. Venofer is for use in adults and children at least 2 years old. If either is present, do not use the liquid. fever. Most people will metabolize medication by half every time it circulates the body. It depends. Side effects are uncomfortable reactions to medications or drugs. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. This medication is given by injection into a vein as directed by your doctor. 4 0 obj Do not exceed 1,500 mg of iron per dosing course. These are not all the side effects that may occur; contact your healthcare provider if you have questions. Ask your doctor or healthcare provider if Venofer is the right choice for you. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Its given by either intravenous (IV) infusion or slow IV injection. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. It is important to get each dose of this medication as scheduled. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. If you have questions about using Injectafer in a child, talk with your doctor. I was surprised too but the Dr said it definitely sounds like a reaction. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Infusion times range from less than 20 minutes to up to 4 hours. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. If you think there has been an overdose, call your poison control center or get medical care right away. Allergic reactions typically occur the first time your body is exposed to a drug. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Examples of thisinclude: Not allside effectslast forever. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Injectafer begins working as soon as it enters your body. For example: Say you weigh 105 pounds (about 48 kilograms). Instead, youll start by receiving just one treatment course of Injectafer. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. The oral form of the drug, called sucroferric oxyhydroxide and used . Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Feraheme also comes as a liquid thats given by IV infusion. But you dont necessarily need to eat these foods unless your doctor tells you to do so. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. But if they become more severe or dont go away, talk with your doctor or pharmacist. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. People from different ethnic backgrounds process medications differently. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. An iron infusion is a way to increase the body's iron levels quickly. Potential injection site discoloration has happened. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. So you wont pick up this medication from a pharmacy. If you have diarrhea while youre taking Injectafer, call your doctor. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Venofer is given as an infusion into a vein. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. FG Trade/E+ sia Getty Images Blood tests may be needed to check for unwanted effects. Someside effectsare temporary or last as long as the person continues takingprescription medicine. The following lists contain some of the key side effects that may occur while taking Injectafer. Selected from data included with permission and copyrighted by First Databank, Inc. We comply with the HONcode standard for trustworthy health information. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. Some may be a better fit for you than others. 2 0 obj Learn more about these, as well as the symptoms, diagnosis, and treatments. Be ready to tell or show what was taken, how much, and when it happened. These pregnancy-related problems include preterm delivery and low birth weight of your infant. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. If your symptoms or health problems do not get better or if they become worse, call your doctor. <> But you likely wont feel the drug working inside of you. The Injectafer dosage your doctor prescribes will depend on your body weight. (See also Notes section.). Data on file, American Regent, Inc. 1. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. With IDA, you have low hemoglobin levels. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. <> Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Here are answers to some frequently asked questions about Injectafer. This may be helped by giving the medication more slowly or at a lower dose. Renal elimination is negligible. HRT, like other medications, does have some side effects and these are thought to be quite common. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. (A generic drug is an exact copy of the active drug in a brand-name medication.) Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. This test measures the amount of hemoglobin in your blood. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Venofer pregnancy and breastfeeding warnings. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur.
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