Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. Isosorbide mononitrate works in two ways. 8.0 out of 10 from a total of Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Isosorbide mononitrate systemic 60 mg (A ID). Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. It might help to take isosorbide mononitrate and dinitrate after meals. Which drugs or supplements interact with isosorbide mononitrate? Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Coenzyme Q-10 Natural Medicines. tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. https://www.uptodate.com/contents/search. 8600 Rockville Pike Drug information provided by: IBM Micromedex. Many people using this medication do not have serious side effects. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Consult your doctor for more details. Store at room temperature away from light and moisture. My cardiologist recommended I get on metropolol. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. This site complies with the HONcode standard for trustworthy health information: verify here. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. What side effects can this medication cause? Follow directions about how much medicine to take. Should I avoid certain foods while taking Isosorbide Mononitrate? Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Alcohol or marijuana (cannabis) can make you more dizzy. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. The extended-release capsule usually is taken once daily. If we combine this information with your protected 2017; doi:10.1016/j.jacc.2016.11.078. May also be prescribed off label for Esophageal Spasm. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Available for Android and iOS devices. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. Try our Symptom Checker Got any other symptoms? Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Store it at room temperature and away from excess heat and moisture (not in the bathroom). (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Liperoti R, et al. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Herbal supplements are natural, so they must be safe, right? You can consult me online for homeopathic treatment. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Bauer B (expert opinion). Do not drive, use machinery, or do anything that needs alertness until you can do it safely. You may opt-out of email communications at any time by clicking on This content does not have an Arabic version. It does not work fast enough to relieve the pain of an angina attack that has already started. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Alcohol can make the side effects from isosorbide worse. All rights reserved. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. GoodRx works to make its website accessible to all, including those with disabilities. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. If you have recently had a head injury or a heart attack. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. We study millions of patients and 5,000 more each day. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. It is used to treat and prevent a wide range of different conditions. Although not all of these side effects may occur, if they do occur they may need medical attention. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Available for Android and iOS devices. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. View all Properly discard this product when it is expired or no longer needed. This is a condition where the heart does not beat as efficiently as it should. If you miss a dose, take it as soon as you remember. Minimally clinically significant. This content does not have an English version. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Never take more than the prescribed dose. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. 1998 Oct;61(10):577-83. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Your health care provider and pharmacist can help you stay away from unsafe interactions. https://naturalmedicines.therapeuticresearch.com. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Patient does not provide medical advice, diagnosis or treatment. Keep this medication in the container it came in, tightly closed, and out of reach of children. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Isosorbide mononitrate helps to prevent angina chest pain from developing. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Dehydration in Buspar, how severe and when it was recovered? Prescription and OTC Isosorbide tablets are also used with other medications to treat heart failure. Browse all drugs on eHealthMe. The table below contains some of the most common ones associated with isosorbide mononitrate. https://naturalmedicines.therapeuticresearch.com. The extended-release tablet usually is taken once daily in the morning. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Background: It can cause your blood pressure to become dangerously low. other information we have about you. Learn to reduce stress through mindful living. isosorbide mononitrate prices. Data were assessed for carryover and time effects. Valerian: A safe and effective herbal sleep aid? It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. Sept. 26, 2022. (2) One in 3 patients never experienced headache from the given dosages. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). In: Current Medical Diagnosis & Treatment 2022. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Mayo Clinic; 2021. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. This branded product is no longer on the market. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Making any changes without doctor's advice can be dangerous. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Diabetes treatment: Can cinnamon lower blood sugar? There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Thirty percent of the patients never experienced headache from the given dosages. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. Do not change the dosing times unless directed by your doctor. . Copyright 2023 IBM Watson Health. In the US - Call your doctor for medical advice about side effects. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Read our editorial policy. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Ask your pharmacist any questions you have about refilling your prescription. Consult your doctor before breast-feeding. This drug may make you dizzy. Bookshelf This is called tolerance, and it cannot be fixed by raising the dose of the medication. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. All rights reserved. Don't drink alcohol while taking isosorbide mononitrate (Monoket). the unsubscribe link in the e-mail. Use of herbal products and potential interactions in patients with cardiovascular diseases. We comply with the HONcode standard for trustworthy health information. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. . Before It does not have such side effects. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Try to keep your regular appointments with your doctor. AskMayoExpert. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. It is also important information to carry with you in case of emergencies. It works to relax your blood vessels. I strongly feel that there is coronary ischemia. Select a condition to view a list of medication options. But only about 25% of people who take herbal supplements tell their health care providers. Does isosorbide mononitrate (Monoket) lower blood pressure? Seek alternatives to the CYP3A4 substrate when possible. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Side effects : headache, mild dizziness Natural Medicines. Botanical medicine A modern perspective. This should pass after a few days. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 2005 - 2023 WebMD LLC. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Isosorbide mononitrate (Monoket) can cause some serious health issues. Selected from data included with permission and copyrighted by First Databank, Inc. We don't support your browser. Limit alcoholic beverages. These side effects may go away during treatment as your body adjusts to the medicine. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Isosorbide mononitrate helps to prevent angina chest pain from developing. National Library of Medicine It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. This product is available in the following dosage forms: There is a problem with It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. It is components of vit. Never give it to other people even if their condition appears to be the same as yours. B complex. It is best not to drink alcohol while you are on isosorbide mononitrate. Normal ecg doesn't rule out heart disease. Nitroglycerin has an average rating of sharing sensitive information, make sure youre on a federal If this worries you, talk to your doctor or pharmacist about other options. Other medications may be prescribed by your doctor for these conditions. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Continue to take isosorbide even if you feel well. Unauthorized use of these marks is strictly prohibited. Real test is coronary angiography. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Review/update the The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. This does not necessarily mean no interactions exist. This content does not have an English version. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . official website and that any information you provide is encrypted 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). This medicine is available only with your doctor's prescription. Avoid combinations; the risk of the interaction outweighs the benefit. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Browse Drugs and Medicines. Do not take more or less of it or take it more often than prescribed by your doctor. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Moderately clinically significant. Do infrared saunas have any health benefits? Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Take the missed dose as soon as you remember it. Let your provider know if they are excessive. Your dose may need to be gradually decreased. https://naturalmedicines.therapeuticresearch.com. All Rights Reserved. Ginkgo. Saw palmetto. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. So get a ct scan brain apart from cardiology workup. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. My EKG showed Assess your symptoms online with our free symptom checker. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This makes it easier for your heart to pump, relieving heart-related chest pain. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. I would rather take the chance of a heart attack than have no quality of life. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Mehta D. Herbal & dietary supplements. What special dietary instructions should I follow? Epub 2006 Mar 22. If headaches continue or become severe, tell your doctor promptly. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Discuss the risks and benefits with your doctor. This content does not have an Arabic version. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Natural Medicines. What conditions does Isosorbide Mononitrate treat? Unless there is a specific reason you need the brand, the generic medication will be a better value. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. https://naturalmedicines.therapeuticresearch.com. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. It is in the nitrate class of drugs. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Headache is often a sign that this medication is working. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Keep all medications away from children and pets. Take your next dose at the regular time. Medicines containing Isosorbide Mononitrate. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Then, there was a two-week placebo washout, after which the alternative treatment was given. All rights reserved. This should pass after a few days. Tolerance is more likely to happen if you don't take your dose at the same time every day. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. No, that's not true all the time. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Do not take a double dose to make up for a missed one. Take the container with you, even if it is empty. Licorice. You may report side effects to the FDA at 1-800-FDA-1088. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. This medication belongs to a class of drugs known as. During pregnancy, this medication should be used only when clearly needed. Am J Ther. On the other hand, the ER version can only help prevent angina. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. Theyre fast, easy-to-use and free! Accessed Sept. 7, 2022. Other side effects not listed may also occur in some patients. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Using this medicine with any of the following medicines is not recommended. It will not treat an angina attack that has already begun. MBBS, MS - General Surgery, mch neuro surgery. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Yet many herbal supplements may interact with heart disease medicines. The effects of this exposure on a nursing infant are unknown. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. The most common side-effect is headache. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain.
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